Inclusion/exclusion criteria and current inclusion center

Inclusion  center (per December 2018)

  • Amsterdam UMC – 1 inclusion
  • Amphia Ziekenhuis Breda – 31 inclusions
  • Medisch Spectrum Twente  – 10 inclusions
  • UMC Utrecht – 56 inclusions
  • Maastricht UMC – 3 inclusions

Inclusion criteria

Exclusion criteria

  • Pulmonary hypertension (>50mmHg)
  • Atrial fibrillation
  • High surgical risk/inoperable patient
  • Left ventricular end systolic dimension > 40mm and one of the following: flail leaflet or LA volume >60 ml/m2 BSA at sinus rhythm
  • eGFR < 30 mL/min
Dutch AMR